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NEW QUESTION # 45
PCT usually rises within 3-6 hours of infection. CRP also increases rapidly following infection, but is not as specific for infection as PCT. A rise in CRP could also occur with SIRS. Lactic acid is usually used to detect and monitor impaired circulation and tissue oxygenation in critically ill patients.
Of the three laboratory tests that are listed, which has proven to be most effective for early differentiation of systemic inflammatory response syndrome (SIRS) from sepsis due to its increase following infection and higher specificity?
- A. Procalcitonin (PCT)
- B. C-reactive protein (CRP)
- C. Lactic acid
NEW QUESTION # 46
Which area of the laboratory can analyze a patient sample and be able to predict their risk of developing a disease?
- A. Clinical chemistry
- B. Immunology
- C. Molecular testing
- D. Blood banking/transfusion medicine
NEW QUESTION # 47
The most likely causes of delayed hemolytic reactions are Kidd system antibodies. Both jka and jkb are often responsible for delayed hemolytic transfusion reactions.
Delayed hemolytic transfusion reactions are usually caused by antibodies directed against what blood group system?
- A. Kidd.
- B. Rh.
- C. ABO
- D. MNS
- E. Kell.
NEW QUESTION # 48
What other component(s) can be shipped together with Fresh Frozen Plasma (FFP)?
- A. platelets
- B. none
- C. frozen RBC's and cryoprecipitate
- D. whole blood
- E. packed RBC's and granulocytes
NEW QUESTION # 49
The intended response is Vitamin B12 and folate deficiencies. Each of these conditions lead to a megaloblastic production of the red blood cells in the bone marrow. Since vitamin B12 and folate are needed in order to produce a synchronous development of the nucleus with the cytoplasm in hematologic cells, oval-macrocytosis often occurs if these nutrients are not in adequate supply within the body. This can also affect neutrophils, allowing for the characteristic hypersegmented nucleus.
The photographic field contains several oval-macrocytes and a hypersegmented neutrophil with greater than 5 nuclear segments. Oval macrocytes are most commonly associated with pernicious anemia and malabsorption syndromes leading to vitamin B12 and folic acid deficiencies.
Clinical information relating to chronic infection, aplastic anemia, and other hematologic maligancies provide the context for the presence of the oval macrocyte.
Macrocytic erythrocytes and hypersegmented neutrophils are not present in thalassemias or in Pelger-Huet anomaly (hyposegmented neutrophils).
Conditions suggested by the macrocytes and the neutrophil in the photograph to the right include which of the following?
- A. Pelger-Huet anomaly
- B. Thalassemia
- C. Vitamin B12 deficiency
- D. Folate deficiency
NEW QUESTION # 50